Agonist antibody that induces human malignant cells to kill one another

Agonist antibody that induces human malignant cells to kill one another.

An attractive, but as yet generally unrealized, approach to cancer therapy concerns discovering agents that change the state of differentiation of the cancer cells. Recently, we discovered a phenomenon that we call "receptor pleiotropism" in which agonist antibodies against known receptors induce cell fates that are very different from those induced by the natural agonist to the same receptor. ...

Agents that look at one another

Despite the fact that epistemic connectives are sometimes interpreted in concrete structures defined by means ofruns and clock time functions, one of the things which strikes one when studying multiagent logics is how abstracttheir semantics are. Contrasting this fact is the fact that real agents like robots in everyday life and virtual charactersin video games have strong links wit...

Drugs that Kill Cancer Stem-like Cells

Talc induces apoptosis in human malignant mesothelioma cells in vitro.

Pleurodesis with talc is an accepted method for the treatment of symptomatic pleural effusions secondary to mesotheliomas. Patients with mesothelioma who have talc-induced pleurodesis have a lower morbidity than do those who do not have pleurodesis. The mechanisms whereby talc mediated these effects were considered to be secondary to a decrease or absence of a pleural effusion. The possibility ...

Cells O Antibody Screening Cells: A novel Approach to Antibody Screening

ABSTRACT        Background and Objectives: Blood transfusion may induce some adverse effects on receivers. Some methods such as antibody screening and cross matching have been suggested to reduce the risk of transfusion complications. However, these methods require commercial antibody screening kits that may also need special equipment. The aim of this study was t...